Red, Blue, & O2 Protocol Stack

Longevity Effect Family! Cameron here.

In our last article, we introduced you to the Red, Blue, & O2 Protocol, which can drastically enhance your mitochondrial health. And if you remember anything about the mitochondria, you’ll know that is a BIG deal for your health and vitality.

As promised, I’m here to provide a sample protocol on how to effectively stack these modalities to get optimal results. But first, let’s take a quick review.

1. Red Light Therapy

Red Light therapy, often called photobiomodulation (PBM) or low-level laser therapy (LLLT), is a powerful tool for boosting health and wellness. This therapy works by delivering targeted wavelengths of red and near-infrared light to improve cellular activity, stimulate collagen production, reduce inflammation, and enhance blood flow.

Our mitochondria absorb this light and convert it into cellular energy boosting the production of Adenosine Triphosphate (ATP).

2. Methylene Blue

Methylene Blue (methylthioninium chloride) was the first antimalarial drug ever used in medicine, and today it is used as a nootropic to increase memory, mood, and longevity.

MB has numerous benefits, but for the sake of this protocol, we are highlighting its incredible ability to improve and optimize mitochondrial function by donating and accepting electrons to the Electron Transport Chain (ETC), which increases ATP production to provide more cellular energy.

3. Hyperbaric Oxygen Therapy

I get asked what a lot what my favorite or most recommended modality would be if I had to choose. The answer is always the same. HBOT and for good reason.

Oxygen is life. When you exponentially increase the amount of oxygen saturated within the body you get incredible benefits. In this case, oxygen is needed as the final stage of creating cellular energy (not to mention it’s also how the body heals itself). No oxygen = no energy = no life. This is why you can’t hold your breath for longer than a few minutes.

HBOT sounds complex, but when you get down to the basics, it’s really just increased pressure + higher oxygen concentration. The body does the rest!

4. Sample Protocol

Combining methylene blue, red light therapy, and hyperbaric oxygen therapy creates a multifaceted approach to enhancing cellular health and overall wellness.

These therapies work together through complementary effects, supporting mitochondrial function, cellular respiration, reducing inflammation, and promoting tissue repair.

A typical protocol in our office would look something like this:

• Methylene Blue IV for immediate absorption.
• Red Light Therapy on the skin (or Infrared Sauna) for 10–20 minutes anytime after IV.
• Hyperbaric Oxygen Therapy for 60 minutes immediately after red light.

This protocol can be used several times a week to maximize results.

Do you have to do it exactly this way to get great benefit? No.

Do you have to come to our office day after day to execute this? Technically no.

Can you create your own version of this protocol at home? Absolutely!

Here’s how

• Get some MB capsules ordered through us at IV Effect — we can even have the pharmacy ship them to you once you are cleared (typically 5mg — 10mg is a good starting point) — If taking orally, it’s recommended to take at least one hour prior to the next step to ensure absorption.
• Buy a red light panel or portable Infrared Sauna — we recommend Platinum LED Therapy Lights & Relax Saunas. OR you can simply go outside and expose as much skin to the sun as possible.
• Other Oxygen Ideas — Breathwork such as Wim Hof Method, sprints, or EWOT (Exercise With Oxygen Therapy)

Well there you have it folks. The Red, Blue, & O2 Protocol. We’re so excited to see how you implement this in your own life, whether through in-office visits, your home adaptations, or a mix of both.

Remember, true wellness is a practice, and even small steps can create big changes over time.

As always, we’re here to guide, support, and cheer you on! Please reach out with any questions, feedback, or success stories — we love hearing from you.

Until next time, keep living well.
— Cameron and the Longevity Effect Team

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